Module Code - Title:
BY4203
-
CELLULAR PATHWAYS AND PATHOPHYSIOLOGY IN HEALTH AND DISEASE
Year Last Offered:
N/A
Hours Per Week:
Grading Type:
N
Prerequisite Modules:
Rationale and Purpose of the Module:
This module provides an in-depth exploration of the medical significance of cellular pathways underlying normal physiological functions and their dysregulation. Building upon the foundational knowledge acquired in Year 1, students will study the molecular mechanisms of cellular processes as they relate to medicine. Students will gain a comprehensive understanding of how healthy cellular pathways maintain organism homeostasis, while alterations in pathways contribute to the pathogenesis of diseases such as cancer, and neurodegenerative conditions.
Syllabus:
The following is indicative of the content to be covered in this syllabus:
- Revision of Cellular Structure and Organelles
- Introduction to Cellular Pathways in disease
- Cell surface receptors and intracellular signalling cascades in disease
- Transcriptional Regulation pathways in pathology
- Cell Cycle Regulation in health and disease
Learning Outcomes:
Cognitive (Knowledge, Understanding, Application, Analysis, Evaluation, Synthesis)
On successful completion of this module, students will be able to:
- Describe the molecular and cellular mechanisms that underlie a range of common diseases such as cancer, metabolic disorders and immune diseases;
- Analyse the process of scientific research and the appraise the role of transforming technologies in advancing our knowledge;
- Critique strategies for translation of research into technologies and treatments;
- Analyse scientific literature, integrate and contrast scientific data from different sources to synthesise new models and hypotheses; participate in scientific discussions.
Affective (Attitudes and Values)
On successful completion of this module, students will be able to:
- Demonstrate reflective practice to integrate knowledge, skills and experience of scientific research.
Psychomotor (Physical Skills)
On successful completion of this module, students will be able to:
N/A
How the Module will be Taught and what will be the Learning Experiences of the Students:
The curriculum has been designed to foster enquiry and self-directed learning among students, by ensuring a that students are guided through the most current research in the area in a supportive learning environment.
This module will be taught via lectures, labs and tutorials with a case study approach to develop students' ability to apply knowledge to clinical and real-life settings. Outside this formal contact the student will be encouraged to develop skills in acquiring information as individual learners as well as working in group learning teams.
This module addresses the graduate attributes of curious (providing knowledge and critical thinking), agile (developing the independent learner) and articulate (developing interpersonal and collaborative skills).
The ethos across the curriculum is to ensure research led teaching. Lecture content will be constantly updated to incorporate new findings in the field of Cell Biology and Cell Signalling.
Research Findings Incorporated in to the Syllabus (If Relevant):
Prime Texts:
George Plopper, PhD; Diana Bebek Ivankovic, PhD (2020)
Principles of Cell Biology, 3rd Edition
, Jones and Bartlett Learning
George Plopper, PhD; David Sharp, PhD; Eric Sikorski (2015)
Lewins Cells, 3rd Edition
, Jones and Bartlett Learning
Other Relevant Texts:
Programme(s) in which this Module is Offered:
BMMESUUFA - BACHELOR OF MEDICINE BACHELOR OF SURGERY
Semester(s) Module is Offered:
Autumn
Module Leader:
raffaele.nicastro@ul.ie