The purpose of this module is to give students a comprehensive understanding of energy metabolism and the metabolic processes involved in nutrient catabolism at a whole body level. This module will critically evaluate selected nutrients and bioactives with a focus on their potential health benefits. It will provide a comprehensive understanding of the aetiology and management of nutrition-related disorders in the clinical setting. The purpose of this module is to: - Provide advanced concepts in nutrient metabolism including an overview of the metabolic pathways involved in energy metabolism, catabolism and anabolism. The control of metabolic reactions. - Outline the metabolism of selected nutrients. Critical evaluation of the evidence on selected nutrients and bioactives and their potential health benefits. - Explore the use of nutrition for health in the clinical setting. Practical case studies will give students a practical understanding of the importance of nutritional management in a range of clinical conditions. As part of the overall assessment, and to further student ability to critique scientific research, a detailed literature review on a relevant research area will be conducted. Students will be expected to prepare a detailed report on their research work and to make a presentation on their findings to enhance communication skills.

1.Overview of energy metabolism for the whole body including carbohydrate, protein and lipid metabolism. 2.Interplay between various metabolic regulatory systems (metabolic and hormonal) and adaption to various metabolic demands (starvation, overfeeding etc.) 3.The importance of physical activity in energy expenditure and the thermic effects of food. 4.Metabolism of selected nutrients and dietary bioactive components in relation to health (including fat- and water-soluble vitamins, essential fatty acids, phytochemicals, prebiotics). 5.Overview of nutritional strategies to manage disease conditions.

On completion the student should be able to: - Demonstrate an in-depth understanding of nutrient metabolism in humans. - Discuss the biochemical and physiological aspects of macro- and micronutrient metabolism at the whole body, tissue and cellular level. - Discuss the latest evidence regarding the roles of selected nutrients and bioactives in relation to human health. - Provide an in-depth, critical review of the evidence in relation to the possible health benefits of selected nutrients and dietary bioactive components. - Evaluate clinical conditions and personal nutritional goals, and apply nutritional strategies to manage disease conditions.

Appreciate the interrelationship between the metabolic processes involved in energy provision and understand the physiological adaptations to metabolic stress and metabolic disorders.

Lectures, tutorials and project based assignments