Module Code - Title:
MT4006
-
TISSUE ENGINEERING
Year Last Offered:
2025/6
Hours Per Week:
Grading Type:
N
Prerequisite Modules:
Rationale and Purpose of the Module:
The rationale of this module is to augment the Biomedical Engineering undergraduate module portfolio with a module in Tissue Engineering and Regenerative Medicine.
The purpose of the module is to cover the physical principles and engineering science associated with Tissue Engineering, encompassing biomaterial selection, tissue scaffold design, bio printing, and cell-matrix interactions.
Syllabus:
Fundamental Principles of Tissue Engineering and regenerative medicine •Biomaterials in tissue Engineering: hydrogels; growth factors; synthetic scaffolds; Stem Cells for Tissue Engineering • Tissue Scaffold design • Scaffold fabrication Bioprinting; Electrospinning; freezedrying • Cell Culture for Tissue Engineering • Cell Proliferation and Migration • Scaffolds for Tissue Based Repair • Bioprinting • Bioreactor Systems and Design • Diffusion & Nutrient Transport Limitations in Tissue Engineered Constructs • Skin Tissue Regeneration • Cartilage Tissue Engineering & Regeneration • Bone Tissue Engineering • Cardiovascular Tissue Engineering • Corneal Tissue Engineering and Replacement • Cell encapsulation •Immunomodulation and protection example Diabetes • Peripheral Nerve Repair • Cell Separation Technology • Gene Therapy • Regenerative Surgery in Orthopaedics & Sports Medicine • Ethical Issues and Considerations for Tissue Engineering
Learning Outcomes:
Cognitive (Knowledge, Understanding, Application, Analysis, Evaluation, Synthesis)
On successful completion of this module it is expected that the students will be able to:
Recognise the key role of tissue engineering in biomedical engineering
Understand the current state of the art, emerging technologies and advances in the field
Provide an insight on biomaterial properties and integration of biomaterials with engineered tissue
Affective (Attitudes and Values)
Support a professional commitment to ethical practice
Appreciate conflicting issues between personal beliefs and ethical considerations
Psychomotor (Physical Skills)
N/A
How the Module will be Taught and what will be the Learning Experiences of the Students:
The module will be taught through an inter-linked and inter-dependent series of lectures and laboratory sessions. Graduate attributes will be developed through a learning process that will be scaffolded through a series of problem based learning assignments in which the latest research findings on the topic will be discussed and critically analysed within the context of student enquiry. The module will be delivered through blended learning and flipped classroom approaches in order to prioritise student active engagement with practical problems over content delivery. The latest technology enhanced learning tools such as slido and SULIS will be used to deliver content in the form of videos and quizzes.
Research Findings Incorporated in to the Syllabus (If Relevant):
Prime Texts:
Fisher, Mikos & Bronzino (2013)
Tissue Engineering:Principles and Practices
, CRC Press
Lanza, Langer & Vacanti (2014)
Principles of Tissue Engineering 4th ed
, Elsevier
Clemens Van Blitterswijk and Jan de Boer (2015)
Tissue Engineering
, Academic press
Other Relevant Texts:
Programme(s) in which this Module is Offered:
BEBIENUFA - BIOMEDICAL ENGINEERING
Semester(s) Module is Offered:
Spring
Module Leader:
maurice.collins@ul.ie